With many injuries, especially in tendons and ligaments, there is an inadequate healing response or the tissue is taken down a degeneration pathway instead. Biologics are able to re-start the healing pathway. They are useful for tendinosis (previously called tendinitis), tendon tears, ligament tears, non-healing stress fractures, chronic nerve entrapments – basically any musculoskeletal or peripheral nerve injury, in which the healing response has been absent or inadequate.